SBP GROUP (01177.HK): TQC3721 Phase III completes enrolment

On 8 October 2026, SBP GROUP (01177.HK) said the Phase III PACER-III trial of its TQC3721 inhalation suspension for COPD in China completed full enrolment.
Key Highlights:
  • TQC3721 is a dual PDE3/4 inhibitor that relaxes airway smooth muscle to improve ventilation and inhibits inflammation.
  • It is available as a nebulized inhalation suspension and a dry powder inhaler, the latter having advanced to Phase II.

NewTimeSpace News: On 8 October 2026, Sino Biopharmaceutical Limited (01177.HK) announced that the pivotal Phase III registration trial (PACER-III) of TQC3721 inhalation suspension for maintenance treatment of chronic obstructive pulmonary disease (COPD) has completed full enrolment. The Class 1 innovative drug is developed by its subsidiary Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

TQC3721 is a dual PDE3/4 inhibitor. PDE3 is highly expressed in airway smooth muscle and PDE4 in inflammatory cells, so the drug relaxes airway smooth muscle to improve ventilation and inhibits inflammation to control disease progression. Available as a nebulized suspension and a dry powder inhaler, the former showed best-in-class potential in Phase II and has completed Phase III enrolment, while the latter has advanced to Phase II. It may become China's first approved domestic inhaled dual PDE3/4 inhibitor.

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