Tyligand Bioscience Ltd. HKEX Listing Application Lapses; Core Candidate Enters Phase 2 Clinical Trials

NewTimeSpace News: The Hong Kong listing application submitted by Tyligand Bioscience Ltd. on 29 January 2026 has lapsed upon expiry of the six-month validity period. CICC acted as the original sole sponsor. Founded in 2017, the Company is a clinical-stage biopharmaceutical firm focused on discovery and development of innovative oncology therapies. Its pipeline includes four drug candidates. The core asset TSN1611, a highly selective oral KRAS G12D inhibitor, is undergoing Phase 2 clinical trials in the US and China.

NewTimeSpace News: The listing application submitted by Tyligand Bioscience Ltd. to the Hong Kong Stock Exchange on 29 January 2026 has lapsed upon expiry of the six-month term. CICC served as the original sole sponsor.

Founded in 2017, the Company is a clinical-stage biopharmaceutical company dedicated to the discovery and development of innovative anti-tumour therapies. As of the latest practicable date, its pipeline comprises four drug candidates: TSN1611, the core candidate in Phase 2 clinical trials; an additional clinical-stage candidate TSN222; and two preclinical candidates TSNA1789 and TSNA3339.

The core candidate TSN1611 is a highly selective oral KRAS G12D inhibitor. As one of the most prevalent oncogenic driver mutations, KRAS G12D has long represented a major therapeutic challenge. TSN1611 is currently being evaluated in Phase 2 clinical trials conducted in the United States and China. The Company plans to advance pivotal registration-enabling clinical trials in China for the treatment of non-small cell lung cancer.

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