Jiangsu Alphamab Oncology-B(09966.HK): Phase II Clinical Trial of JSKN033 as First-line Therapy for Advanced Cervical Cancer Completes First Patient Dosing

NewTimeSpace News: Alphamab Oncology announced on May 13 that the Phase II clinical study of JSKN033, a high-concentration subcutaneous fixed-dose combination consisting of a HER2 bispecific antibody-drug conjugate and a PD-L1 immune checkpoint inhibitor, in combination with platinum-based chemotherapy with or without bevacizumab as first-line treatment for advanced cervical cancer, has completed the first patient dosing.

NewTimeSpace News: On May 13, 2026, Jiangsu Alphamab Oncology-B(09966.HK) issued a voluntary announcement stating that the Phase II clinical trial (JSKN033-202) of JSKN033 combined with platinum-based chemotherapy, with or without bevacizumab, for the first-line treatment of advanced cervical cancer has completed the first patient dosing.

According to the announcement, JSKN033 is the world’s first high-concentration subcutaneous injectable combination formulation developed by Alphamab Oncology. It consists of JSKN003, a HER2 bispecific ADC, and envafolimab, a PD-L1 domain antibody. It features differentiated advantages including seconds-level subcutaneous administration and low haematological toxicity.

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