CKLIFE SCIENCES (00775.HK): Establishes Wholly-Owned Subsidiary Sequencio Focused on Therapeutic Cancer Vaccine Development

NewTimeSpace: CK Life Sciences Int'l., (Holdings) Inc. (00775.HK) announced the establishment of Sequencio (Shunpu Pharmaceutical Technology Co., Ltd.), a wholly-owned subsidiary dedicated to the development of its portfolio of therapeutic cancer vaccines.Sequencio’s preclinical pipeline includes vaccine candidates targeting TROP2, PRAME, PD-L1, B7-H3 and Claudin 6. Among them, the TROP2-targeted vaccine demonstrated complete tumor growth inhibition in preclinical studies.
NewTimeSpace News: CK Life Sciences Int'l., (Holdings) Inc. (00775.HK) issued a voluntary announcement on March 10, 2026, announcing the establishment of Sequencio, a wholly-owned subsidiary focused on advancing the development of its portfolio of therapeutic cancer vaccines.
Sequencio consolidates the Group’s therapeutic cancer vaccine R&D programs into a dedicated platform, reflecting the Company’s strategic commitment to expanding in this emerging field of cancer immunotherapy.
Sequencio focuses on developing therapeutic vaccines that activate a patient’s own immune system to fight cancer cells, aiming to achieve durable and stable disease remission with a favorable safety profile, addressing key limitations of current standard-of-care therapies.
Sequencio has a long-term vision:to redefine the cancer treatment paradigmfrom inducing temporary tumor shrinkage toward long-term controllable remission via the immune system.
Vaccine research and design will be conducted by an in-house team, combining internal scientific capabilities and external partnerships to accelerate overall development.
Sequencio’s preclinical pipeline includes the Company’s investigational cancer vaccine targeting Trophoblast Cell-Surface Antigen 2 (TROP2).
In preclinical mouse studies of breast cancer and colorectal cancer, this candidate vaccine induced robust T-cell immune responses and achieved100% complete tumor growth inhibition.
The pipeline also includes vaccine candidates targeting Preferentially Expressed Antigen in Melanoma (PRAME), Programmed Death-Ligand 1 (PD-L1), the B7-H3 immune checkpoint, and Claudin 6.
With Sequencio, TransCode and Dogwood now under its umbrella, the Company has built a diversified R&D platform covering both early- and late-stage projects, focusing on areas of unmet medical need.
Previously, in 2024, the Company completed a transaction with Dogwood Therapeutics, a Nasdaq-listed company, and now holds a majority stake in Dogwood.
In 2025, the Company sold seviprotimut-L, a late-stage melanoma vaccine, to TransCode Therapeutics, another Nasdaq-listed company, in exchange for an equity stake.

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