Insilico Medicine Launches Hong Kong's Largest Biopharma IPO of the Year with HKIC as Strategic Investor

On December 30, 2025, Insilico Medicine, hailed as "the first AI-driven pharmaceutical stock on the Hong Kong stock market" and a strategic investment of the Hong Kong Investment Corporation Limited (HKIC), was listed on the Main Board of the Hong Kong Exchanges and Clearing Limited (HKEX). With a total fundraising of HK$2.277 billion, it has claimed the title of the largest IPO in the biopharmaceutical sector of the Hong Kong stock market in 2025, and its share price delivered an impressive performance on the debut day. It is reported that Biren Technology, another portfolio company of HKIC, is also set to list on the HKEX on January 2, 2026, which indicates that the effectiveness of HKIC’s diversified strategic investment layout continues to unfold.

On December 30, 2025, Insilico Medicine (stock code: 03696.HK), a clinical-stage biopharmaceutical technology company driven by generative artificial intelligence and hailed as "the first AI-driven pharmaceutical stock on the Hong Kong stock market", was officially listed on the Main Board of the Hong Kong Exchanges and Clearing Limited (HKEX). The stock delivered a robust performance on its debut day, opening at HK$35, representing a 45.53% surge from the offer price, and closing at HK$29.98 with a 24.66% gain. Its market capitalization once exceeded HK$19.5 billion. 

As a strategic investment project of the Hong Kong Investment Corporation Limited (HKIC), the company raised a total of HK$2.277 billion in this IPO, making it the largest IPO in the biopharmaceutical sector of the Hong Kong stock market in 2025. 

The successful listing of Insilico Medicine not only validates its own commercialization capabilities but also demonstrates HKIC’s strategic investment acumen in the biotech track. As a wholly-owned investment platform of the Hong Kong Special Administrative Region (HKSAR) Government, HKIC focuses on the layout of high-quality projects in the science and technology innovation field. The listing of its strategically invested project on the Hong Kong stock market will further inject vitality into the latter’s biopharmaceutical sector. 

Biren Technology, known as "the first GPU stock on the Hong Kong stock market", is also scheduled to be listed on the HKEX on January 2, 2026. It is reported that HKIC also invested in Biren Technology in an earlier financing round. According to HKIC’s 2024 Annual Report, multiple investment projects under its portfolio are in the process of advancing their IPOs, and the market is expected to see more HKIC-invested projects go public one after another in the future. 

The increasing number of successful listings of HKIC’s invested projects has confirmed the corporation’s strategic vision and long-term layout. As Ms. Chan Ka Hei, Chief Executive Officer of HKIC, commented, "Genuine patient capital is by no means about waiting passively for returns; instead, it is about paving the way with purposeful, proactive and responsible actions—by teaming up with the right people in the right track to accomplish the right cause." 

As of December 2025, HKIC has invested in over 160 projects, with every HK$1 of its investment leveraging HK$6 of long-term capital in the market. For HKIC, the listing of Insilico Medicine is merely a starting point. Its true value lies not in the brilliance of a single breakthrough, but in the ability to light up the entire galaxy of high-quality projects.

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